abstract：:The nucleotide sequence of the matrix gene (M) of a recently identified morbillivirus, phocid distemper virus (PDV), was determined and the amino acid composition deduced. The M gene of PDV shared many characteristics with the corresponding gene in other morbilliviruses. The nucleotide homology with the closely relate...

journal_title：Virus research

authors： Sharma B,Norrby E,Blixenkrone-Möller M,Kövamees J

更新日期：1992-04-01 00:00:00

abstract：:Inhibition of the function of the M2 protein by amantadine can cause a conformational change in the haemagglutinin (HA) of H7 influenza A viruses and the consequent expression of the low pH form of the glycoprotein on the surface of virus-infected cells. Immunofluorescence studies showed that this conversion occurs sh...

journal_title：Virus research

authors： Ciampor F,Thompson CA,Grambas S,Hay AJ

更新日期：1992-03-01 00:00:00

abstract：:Cold-passaged (CP) mutants derived from the JS strain of wild type wt parainfluenza type 3 virus (PIV3) are being evaluated as candidate live virus vaccines. The wt virus was serially passaged 45 times at low temperature and mutant clones with the cold-adapted (CA), temperature-sensitive (ts), and attenuation (ATT) ph...

journal_title：Virus research

authors： Hall SL,Stokes A,Tierney EL,London WT,Belshe RB,Newman FC,Murphy BR

更新日期：1992-03-01 00:00:00

abstract：:The mammalian reoviruses possess a genome composed of 10 double stranded RNA segments. The serotype 1 strain Lang M1 segment was sequenced and compared to the published type 3 sequence. Both segments were 2304 base-pairs long coding for the mu 2 protein predicted to be 736 amino acids long. The sequences were highly c...

journal_title：Virus research

authors： Zou S,Brown EG

更新日期：1992-02-01 00:00:00

abstract：:The T-helper response to the measles virus nucleoprotein (NP) has been studied in mice. The T-cell proliferative response was measured in lymphocytes from mice immunized with either a vaccinia measles-NP recombinant virus or a mouse neuro-adapted measles virus. A T-cell response was obtained with lymphocytes from H2d ...

journal_title：Virus research

authors： Giraudon P,Buckland R,Wild TF

更新日期：1992-01-01 00:00:00

abstract：:All entero- and rhinovirus RNAs sequenced thus far possess A and U residues at positions corresponding to nucleotides 480 and 525, respectively, of poliovirus type 1. These two nucleotides have been proposed previously to form a base pair. The single exception to this rule appears to be the Sabin type 1 strain, which ...

journal_title：Virus research

authors： Muzychenko AR,Lipskaya GYu,Maslova SV,Svitkin YV,Pilipenko EV,Nottay BK,Kew OM,Agol VI

更新日期：1991-10-01 00:00:00

abstract：:Certain insect cell lines have been shown to be permissive (TN-368) or semipermissive (IPLB-LD-652Y) for Autographa californica nuclear polyhedrosis virus (AcMNPV) replication (McClintock et al., 1986b). In this report DNA-binding proteins were identified in such cell:virus systems by hybridizing Western blots contain...

journal_title：Virus research

authors： McClintock JT,Guzo D,Guthrie KP,Dougherty EM

更新日期：1991-07-01 00:00:00

abstract：:We have used the polymerase chain reaction (PCR) to obtain sensitive detection and identification of poliovirus RNA genomes. Primer pairs were designed to permit identification of each Sabin poliovaccine strain by the electrophoretic mobilities of the amplified DNA products (Sabin 1: 97 bp; Sabin 2: 71 bp; Sabin 3: 44...

journal_title：Virus research

authors： Yang CF,De L,Holloway BP,Pallansch MA,Kew OM

更新日期：1991-07-01 00:00:00

abstract：:A recombinant baculovirus containing a cDNA which encodes haemagglutinin-neuraminidase (HN) of Newcastle disease virus (NDV) was constructed. Spodoptera frugiperda cells infected with this recombinant virus produced a large amount of HN glycoprotein similar to the authentic HN in size. The recombinant HN glycoprotein ...

journal_title：Virus research

authors： Niikura M,Matsuura Y,Hattori M,Onuma M,Mikami T

更新日期：1991-06-01 00:00:00

abstract：:Earlier studies from this laboratory have shown that infection of vascular cells with herpes simplex virus 1 or 2 (HSV-1, HSV-2) results in the differential suppression of extracellular matrix proteins including fibronectin (FN), type IV collagen, thrombospondin (TSP) and Factor VIII von Willebrand protein. The presen...

journal_title：Virus research

authors： Brinker JM,Ziaie Z,Kefalides NA

更新日期：1991-05-01 00:00:00

abstract：:DNA clones representing the small genomic segment of Nephropathia epidemica virus strain Hällnäs B1 (NEV) and Hantaan virus strain 76-118 (HTV) encoding their nucleocapsid proteins were inserted into the E. coli vector pIN-III-ompA for secretion of proteins into the periplasmic space. The complete HTV and NEV nucleoca...

journal_title：Virus research

authors： Gött P,Zöller L,Yang S,Stohwasser R,Bautz EK,Darai G

更新日期：1991-03-01 00:00:00

abstract：:A temperature-sensitive mutant of the Moloney murine leukemia virus-TB, ts1, causes hindlimb paralysis and immunodeficiency in mice. At the restrictive temperature, the envelope precursor polyprotein, gPr80env, is inefficiently processed intracellularly, and this is associated with the neurovirulence of ts1. To test t...

journal_title：Virus research

authors： Yu Y,Kamps CA,Yuen PH,Wong PK

更新日期：1991-03-01 00:00:00

abstract：:It was previously reported that during serial passage of a BHK-derived cell line persistently infected with foot-and-mouth disease virus, (termed C1-BHK-Rc1) the virus became increasingly more virulent for BHK-21 cells (de la Torre et al 1988). Virus strains isolated from different cell passage levels were tested for ...

journal_title：Virus research

authors： Díez J,Hofner M,Domingo E,Donaldson AI

更新日期：1990-12-01 00:00:00

abstract：:Infection by the human immunodeficiency virus type 1 (HIV-1) is initiated through interaction of its exterior envelope glycoprotein gp120 with the CD4 receptor on target cells. To address the possible role of N-glycosylation of HIV-1 gp120 in binding CD4, we mutated different conserved N-glycosylation site Asn-residue...

journal_title：Virus research

authors： Dirckx L,Lindemann D,Ette R,Manzoni C,Moritz D,Mous J

更新日期：1990-12-01 00:00:00

abstract：:The protein and glycoprotein composition of a sucrose gradient fraction from vaccinia infected cells treated with rifampicin was studied. This particulate fraction contained cytoplasmic membranes and pleomorphic membranous structures. The glycoproteins (89, 42 and 20-23 kDa, respectively) were identified as the same g...

journal_title：Virus research

authors： Payne LG,Kristensson K

更新日期：1990-08-01 00:00:00

abstract：:Adenoviruses, types 2 and 12 induce amplification of SV40 DNA sequences in cells of the SV40-transformed human newborn kidney cell line, NB-E. Similarly, integrated hepatitis B virus DNA sequences in the human hepatoma cell line, PLC/*PRF/5, and bovine papillomavirus (BPV) DNA sequences in BPV-transformed mouse cells ...

journal_title：Virus research

authors： Schlehofer JR,zur Hausen H

更新日期：1990-08-01 00:00:00

abstract：:Eighteen monoclonal antibodies were produced against three Australian bovine enterovirus serogroups. Based on their binding patterns to 14S subunits, natural empty capsids and virions of 4 selected viral isolates (K2577, SL305, 66/27, J2129) in two types of quantitative ELISAs, the 18 antibodies were shown to belong t...

journal_title：Virus research

authors： Zhang AQ,Burgess GW

更新日期：1990-07-01 00:00:00

abstract：:The complete cDNA sequence corresponding to the genomic RNA of a South American strain of potato virus X (PVXc) is reported. The sequence (6432 nucleotides) contains five open reading frames coding for polypeptides with molecular weights of 165.3, 24.3, 12.3, 7.6 and 25.0 and displays an overall homology of 77.4% with...

journal_title：Virus research

authors： Orman BE,Celnik RM,Mandel AM,Torres HN,Mentaberry AN

更新日期：1990-07-01 00:00:00

abstract：:Persisting DNA of parvovirus H-1 could be demonstrated in cells of two human lymphoma cell lines, the Burkitt lymphoma cell line BL2 and the T-cell leukemia cell line Jurkat which survived infection with parvovirus H-1. Persistence of H-1 DNA rendered the cells resistant to a second H-1 infection. This resistance to H...

journal_title：Virus research

authors： Faisst S,Bartnitzke S,Schlehofer JR,zur Hausen H

更新日期：1990-06-01 00:00:00

abstract：:Two lines of LLC-MK2 cells persistently infected with human parainfluenza virus 3 (HPIV-3) have been maintained in culture for approximately 3 years. Subgenomic RNAs (putative defective interfering particle genomes) were detected in virions released from both persistently infected cultures. In one of the persistently ...

journal_title：Virus research

authors： Murphy DG,Dimock K,Kang CY

更新日期：1990-04-01 00:00:00

abstract：:Plasmids containing the varicella zoster virus (VZV) open reading frames (ORFs) 61 and 62 were used in a transient co-transfection assay to test for trans-activation of the VZV and herpes simplex virus type 1 (HSV-1) thymidine kinase (tk) promoters. The trans-activating potential of the polypeptides encoded by these V...

journal_title：Virus research

authors： Cabirac GF,Mahalingam R,Wellish M,Gilden DH

更新日期：1990-01-01 00:00:00

abstract：:Cell lines were constructed which permanently express influenza virus-specific RNA. Two approaches were followed. C127 cells were transformed with bovine papilloma virus (BPV) vectors and the resulting cell lines were found to inhibit the replication of influenza virus at low multiplicity of infection (MOI 0.05). Howe...

journal_title：Virus research

authors： Leiter JM,Krystal M,Palese P

更新日期：1989-10-01 00:00:00

abstract：:Thogoto (THO) virus infections of Rhipicephalus appendiculatus ticks were examined using tick hosts immune to the virus. In the first set of experiments, ticks were infected by feeding on viraemic hamsters. Inter-stadial infection of THO virus was not affected when ticks ingested a virus-immune bloodmeal but there was...

journal_title：Virus research

authors： Jones LD,Nuttall PA

更新日期：1989-10-01 00:00:00

abstract：:C167, a mutant derived from the XJC13 strain of Junin virus, is highly attenuated in its pathogenic properties for newborn mice. Whereas 10(2).PFU of XJC13 injected intracerebrally killed 100% of two-day-old mice, the mutant showed no detectable lethality. Survival of mice infected with C167 was associated with a redu...

journal_title：Virus research

authors： Scolaro LA,Mersich SE,Damonte EB

更新日期：1989-08-01 00:00:00

abstract：:We here report the results of an investigation of the effect of interferon on the establishment of new infections by a retrovirus. For this study, we used an infectious but replication-incompetent retrovirus carrying a drug-resistance gene and assayed for infectivity by measuring drug-resistant colony formation. Mouse...

journal_title：Virus research

authors： Kumar R,Sen GC

更新日期：1989-08-01 00:00:00

abstract：:Japanese encephalitis virus (JEV)-specific RNAs (including 42S RNA) were synthesized in subcellular fractions prepared from infected C6/36 cells. This in vitro RNA synthesis essentially required Mg2+ and four ribonucleotides, and it was enhanced by K+. The amounts of RNA synthesized in vitro (in extracts from JEV-infe...

journal_title：Virus research

authors： Takegami T,Hotta S

更新日期：1989-08-01 00:00:00

abstract：:Recombinant clones containing all or portions of the bovine papillomavirus (BPV) upstream regulatory region (URR) were constructed. When analyzed by polyacrylamide gel electrophoresis, the cloned URR sequences exhibited electrophoretic properties characteristic of DNA containing bend sites. Two distinct bend centers w...

journal_title：Virus research

authors： Wilson VG

更新日期：1989-05-01 00:00:00

abstract：:The A antigen gene from a very virulent strain of Marek's disease virus, RB-1B, has been cloned and the nucleotide sequence determined. The predicted amino acid sequence showed 99% identity to that determined for the MDV GA A antigen (Coussens and Velicer, J. Virol. 62, 2373-2379, 1988) over all but the carboxy-termin...

journal_title：Virus research

authors： Binns MM,Ross NL

更新日期：1989-04-01 00:00:00

abstract：:Fifteen stable mouse spleen cell myeloma hybrids (hybridomas) producing monoclonal antibodies to rinderpest virus proteins were produced. The specificity of these monoclonal antibodies was established by radioimmunoprecipitation followed by polyacrylamide gel analysis and immunofluorescence. Nine antibodies were speci...

journal_title：Virus research

authors： Bhavani K,Karande AA,Shaila MS

更新日期：1989-04-01 00:00:00

abstract：:The nucleotide sequences of the nucleoprotein (NP) genes of fowl plague virus (FPV) and of a temperature-sensitive (ts) mutant (ts81) derived therefrom have been determined. The ts81-NP nucleotide sequence possesses a single nucleotide substitution in comparison to the wild type. This causes an amino acid exchange at ...

journal_title：Virus research

authors： Mandler J,Scholtissek C

更新日期：1989-02-01 00:00:00

abstract：:Human recombinant alpha interferon, A/D, significantly reduced the replication and cell fusion induced by herpes simplex virus type 1 in monkey cells. Thin-section electron microscopy of interferon-treated monkey cells showed distinct assembly of nucleocapsids within the nucleus. Analysis of virus-specific proteins by...

journal_title：Virus research

authors： Chatterjee S,Whitley RJ

更新日期：1989-01-01 00:00:00

abstract：:Vaccines against parainfluenza (PIV) and respiratory syncytial viruses (RSV) that are currently being developed include both live and subunit vaccines. Candidate live PIV vaccines that have been found to be attenuated and efficacious in rodents or primate models are (1) cold-adapted, temperature-sensitive mutants of P...

journal_title：Virus research

authors： Murphy BR,Prince GA,Collins PL,Van Wyke Coelingh K,Olmsted RA,Spriggs MK,Parrott RH,Kim HW,Brandt CD,Chanock RM

更新日期：1988-08-01 00:00:00

abstract：:Nucleic acid probes prepared directly from bluetongue virus (BTV) genomic double-stranded RNA (dsRNA) have been used to identify the functionally equivalent genome segments from six distinct isolates of BTV after their separation in both agarose and polyacrylamide gel electrophoresis systems. Variations in the rate, a...

journal_title：Virus research

authors： Pedley S,Mohamed ME,Mertens PP

更新日期：1988-06-01 00:00:00

abstract：:Northern blot analysis revealed the presence of varicella-zoster virus (VZV) gene 27 transcripts in infected cells. The Sal I-G DNA fragment, located in the unique long segment of the VZV genome and containing overlapping genes 26 and 27, was analyzed in an in vitro transcription-translation system. Translation of RNA...

journal_title：Virus research

authors： Mahalingam R,Wellish M,Cabirac G,Gilden D,Vafai A

更新日期：1988-05-01 00:00:00

abstract：:The uptake of porcine parvovirus (PPV) into host cells, permissive or nonpermissive for PPV replication, was monitored by autoradiography, immunofluorescent microscopy, and dual parameter flow cytometry. While both permissive and nonpermissive cells selectively took up the light (activated) form of the virus from a mi...

journal_title：Virus research

authors： Ridpath JF,Mengeling WL

更新日期：1988-04-01 00:00:00

abstract：:A cloned cDNA (1.65 kb) containing the complete glycoprotein gene of the Josiah strain of Lassa virus was inserted into the thymidine kinase (TK) gene of the New York Board of Health (WYETH) strain of vaccinia virus. The Lassa virus glycoprotein precursor, GPC, and the posttranslational cleavage products, G1 and G2, w...

journal_title：Virus research

authors： Auperin DD,Esposito JJ,Lange JV,Bauer SP,Knight J,Sasso DR,McCormick JB

更新日期：1988-02-01 00:00:00

abstract：:A variant clone of Snyder-Theilen feline sarcoma virus (ST-FeSV) encoding a polyprotein with a molecular weight of approximately 104 kDa (P104) was compared to the P85 encoding prototype clone of ST-FeSV. Analysis of chimeric genes constructed with the viral oncogenes of the two clones indicated that the variant clone...

journal_title：Virus research

authors： Van Groningen JJ,Van den Ouweland AM,Verbeek JS,van der Kemp AW,Bloemers HP,Van de Ven WJ

更新日期：1987-11-01 00:00:00

abstract：:Despite the fact that cells infected with wild type vaccinia virus synthesize viral DNA and assemble progeny virus particles within the cytoplasm, the host cell nucleus is required for a productive infection. Recent evidence suggests that vaccinia virus selectively recruits components from the host cell nucleus into t...

journal_title：Virus research

authors： Moyer RW

更新日期：1987-09-01 00:00:00

abstract：:Hepatitis A virus (HAV) is an important human pathogen causing hepatitis, with high incidence in developed as well as in developing countries. No vaccines are available. In order to determine the primary structure of the HAV genome, we have prepared cDNAs from viral RNA and cloned these into plasmid pBR322. These clon...

journal_title：Virus research

authors： Paul AV,Tada H,von der Helm K,Wissel T,Kiehn R,Wimmer E,Deinhardt F

更新日期：1987-08-01 00:00:00

abstract：:The effect of three lysosomotropic compounds, chloroquine, monensin and NH4Cl, on the replication of foot-and-mouth disease virus (FMDV) type A12 was studied. Viral replication was almost totally inhibited by 0.5 mM chloroquine, 50 microM monensin, or 25 mM NH4Cl. Monensin and NH4Cl affected replication when added eit...

journal_title：Virus research

authors： Baxt B

更新日期：1987-05-01 00:00:00